Exosomal TACSTD2 promotes invasion, metastasis and glycolysis in ovarian cancer
TACSTD2, which can be detected in ovarian cancer-derived exosomes, plays an important role in the invasion, migration and glycolysis in ovarian cancer. Furthermore, we have discovered that TACSTD2 may promote the progression of ovarian cancer by regulating glycolysis. Further research will enable its potentially prognostic marker and therapeutic target for ovarian cancer.
Authors
- Yanyu Li (ORCID: https://orcid.org/0000-0003-1240-4785)
- Bei Zhang (ORCID: https://orcid.org/0000-0002-7494-072X)
- Qisheng Cheng
- Joseph Adu‐Amankwaah (ORCID: https://orcid.org/0000-0003-2155-0864)
- Zhiping Yin (ORCID: https://orcid.org/0000-0001-8679-5251)
- Qing Wang (ORCID: https://orcid.org/0000-0001-7698-1317)
- Xinyuan Zhang (ORCID: https://orcid.org/0000-0002-1737-6069)
- Jingbo Zhang (ORCID: https://orcid.org/0000-0003-4816-7283)
- Meng Wang (ORCID: https://orcid.org/0009-0008-6353-126X)
- Xueyan Zhou (ORCID: https://orcid.org/0000-0001-8047-4545)
Institutions
- Xuzhou Medical College (CN)
- Soochow University (CN)
- Xuzhou Central Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1007/s12672-025-04041-6
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00