Exploring Demographic, Clinical, Surgical, and Imaging Features in Relation to CDKN2A/B Status in Meningiomas
In this cohort, demographic, clinical, or radiological features did not reliably predict CDKN2A/B deletion. Several deletion-positive meningiomas were classified as grade 1 or 2, underscoring the disconnect between morphology and molecular grading. These findings support universal CDKN2A/B testing for accurate WHO classification and risk assessment.
Authors
- Ory Haisraely
- Anton Wohl (ORCID: https://orcid.org/0000-0002-5294-1326)
- Hanan Abofani
- Ahmad Maswadeh (ORCID: https://orcid.org/0000-0002-6568-6395)
- Moshe Attia (ORCID: https://orcid.org/0000-0002-8150-8425)
- Zvi R. Cohen (ORCID: https://orcid.org/0000-0002-0208-5170)
- Tehila Kaisman‐Elbaz (ORCID: https://orcid.org/0000-0002-0658-9624)
- Alisa Talianski
- Ofir Ben-Moyal
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Sheba Medical Center (IL)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.wneu.2025.124699
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00