Serum Biomarkers in Advanced-Stage AIDS-Associated Kaposi Sarcoma in Resource Limited Settings
Pre-treatment biomarker levels were associated with greater KS tumor burden but not with KS response to chemotherapy + ART in people with advanced AIDS-KS. Differential levels of several serum biomarkers were noted on treatment in progressors and non-progressors, suggesting that increased tumor burden was associated with higher levels of inflammation and immune activation.
Authors
- Mina C. Hosseinipour (ORCID: https://orcid.org/0000-0003-2174-313X)
- Thomas Campbell (ORCID: https://orcid.org/0000-0002-2325-4674)
- Carlee Moser (ORCID: https://orcid.org/0000-0001-5601-9112)
- Margaret Borok (ORCID: https://orcid.org/0000-0002-1234-0913)
- Wadzanai Samaneka (ORCID: https://orcid.org/0000-0003-0215-9309)
- Naftali Busakhala (ORCID: https://orcid.org/0000-0002-1229-3475)
- Susan E. Krown (ORCID: https://orcid.org/0000-0003-3395-062X)
- Patrick MacPhail
- Mulinda Nyirenda (ORCID: https://orcid.org/0000-0003-2037-7449)
- Marta Epeldegui (ORCID: https://orcid.org/0000-0002-7605-5994)
- Otoniel Martı́nez-Maza (ORCID: https://orcid.org/0000-0003-1364-0675)
- Josphat Kosgei (ORCID: https://orcid.org/0000-0002-0106-524X)
- Younjung Choi
Institutions
- University of North Carolina at Chapel Hill (US)
- Memorial Sloan Kettering Cancer Center (US)
- Harvard University (US)
- Moi University (KE)
- University of Zimbabwe (ZW)
- University of Malawi (MW)
- University of California, Los Angeles (US)
- University of the Witwatersrand (ZA)
- Kenya Medical Research Institute (KE)
- University of Colorado Denver (US)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1097/qai.0000000000003805
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00