Identification of SAMD9 as an adaptive response gene to environmental changes and its association with overall survival and immunotherapeutic response in glioblastoma
SAMD9 emerges as an adaptive response gene to environmental changes, exhibiting a significant immunomodulatory function, which highlights its promise as a therapeutic target for IDH-wildtype glioblastoma.
Authors
- Chang Lei (ORCID: https://orcid.org/0000-0002-6341-7677)
- Kaidi Yang (ORCID: https://orcid.org/0000-0003-3297-0266)
- Shihui Fu (ORCID: https://orcid.org/0000-0001-6707-9049)
- Min Luo (ORCID: https://orcid.org/0000-0001-5732-4848)
- Weizhen Bi
- Yibo Li (ORCID: https://orcid.org/0000-0002-9640-4493)
- Fan Li (ORCID: https://orcid.org/0009-0009-6274-6100)
Institutions
- Army Medical University (CN)
- People's Liberation Army 401 Hospital (CN)
- Southwest Hospital (CN)
- Hainan 301 Hospital (CN)
- Sanya Central Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Central Hospital of Wuhan (CN)
- Sanya University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s12935-025-04068-3
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00