A novel interleaved TMS-MRS approach with standard MRI hardware
Interleaved TMS-MRS is feasible with standard MRI hardware in TRD patients, enabling in-vivo detection of acute neurochemical changes during stimulation. This method offers a new avenue for probing excitatory/inhibitory balance, neuronal metabolism, and treatment mechanisms.
Authors
- Benjamin Davidson (ORCID: https://orcid.org/0000-0001-5264-1190)
- Jamie Near (ORCID: https://orcid.org/0000-0003-3516-936X)
- Sean M. Nestor (ORCID: https://orcid.org/0000-0002-8848-5027)
- Peter Truong
- Martin Tik (ORCID: https://orcid.org/0000-0002-6571-4413)
- Clement Hamani (ORCID: https://orcid.org/0000-0002-7586-2487)
- Nir Lipsman (ORCID: https://orcid.org/0000-0002-4820-3056)
- Maria Vasileiadi
- Christopher B. Pople (ORCID: https://orcid.org/0000-0002-7014-3280)
- Peter Giacobbe
Institutions
- Sunnybrook Health Science Centre (CA)
- Sunnybrook Research Institute
- Medical University of Vienna (AT)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.brs.2025.102997
- Citations
- 1
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Fondation Brain Canada