Effects of nicorandil on inflammatory response, oxidative stress and myocardial fibrosis after myocardial infarction
Nicorandil attenuates myocardial inflammation, oxidative stress and myocardial fibrosis levels by activating ATP-sensitive potassium channels (K-ATP), thereby improving post-MI cardiac remodeling and preserving cardiac function.
Authors
- Jiesen Lei
- Li Hu (ORCID: https://orcid.org/0000-0001-5796-5143)
- Junrong Peng
- Mei Huang (ORCID: https://orcid.org/0000-0001-8266-4334)
- Tengxiao Xiang
- Xiaojia Dai
- Zhihong Yang (ORCID: https://orcid.org/0000-0002-4133-5099)
- Peng Xiao (ORCID: https://orcid.org/0000-0003-1854-0585)
- R. Li (ORCID: https://orcid.org/0009-0008-3205-574X)
Institutions
- Fuling Center Hospital of Chongqing (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s12872-025-05270-x
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00