The right kind of rarefaction: Coronary microvascular remodeling in right ventricle failure
Capillary rarefaction is a measurable histopathologic feature in explanted RV tissue that correlates with functional indices of RV performance. Our proof-of-concept findings suggest CMD may contribute to RV systolic dysfunction independent of PH subtype.
Authors
- Andrew P. Stein (ORCID: https://orcid.org/0000-0001-6896-5405)
- Katharine Clapham (ORCID: https://orcid.org/0000-0003-3659-4755)
- Avital Schurr (ORCID: https://orcid.org/0000-0001-5303-2071)
- M. Schwietert
- Sheila Talbot
- Leonid Mirson
- Andrew J. Bryant (ORCID: https://orcid.org/0000-0001-9433-3049)
- Kirk D. Jones (ORCID: https://orcid.org/0000-0002-0275-3503)
- Ellen C. Keeley (ORCID: https://orcid.org/0000-0003-2915-4751)
- Dolores Petty
- Angela P. Presson (ORCID: https://orcid.org/0000-0001-7400-3923)
- Andrew H. Baird (ORCID: https://orcid.org/0000-0001-8504-4077)
- Alex M. Parker (ORCID: https://orcid.org/0000-0003-4170-2976)
- Kimberly Dumoff
- Jeremy A. Mazurek (ORCID: https://orcid.org/0000-0002-3332-0102)
- Andrew James Murphy (ORCID: https://orcid.org/0000-0001-7039-7777)
- Cyrus Vahdatpour (ORCID: https://orcid.org/0000-0002-8917-2807)
- S. Hansen (ORCID: https://orcid.org/0009-0005-5844-440X)
- John Ryan (ORCID: https://orcid.org/0000-0002-9203-5512)
- Priti Lal (ORCID: https://orcid.org/0000-0003-2193-9968)
- Zhining Ou (ORCID: https://orcid.org/0000-0002-7353-6872)
- Steven M. Kawut
- Dylan Miller
Institutions
- Brigham Young University (US)
- University of Alabama at Birmingham Hospital (US)
- Thomas Jefferson University (US)
- Baylor College of Medicine (US)
- University of Utah (US)
- Pennsylvania Hospital (US)
- University of Florida Health (US)
- University of Alabama at Birmingham (US)
- University of Florida (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- JHLT Open
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.jhlto.2025.100459
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00