Prognostic role of prognostic nutritional index change in patients with extensive stage small cell lung cancer treated with platinum-based chemotherapy

Dynamic changes in PNI are significantly associated with prognosis in extensive-stage SCLC. Patients with low pre- and post-treatment PNI values exhibited worse outcomes, while consistently high PNI predicted better survival. This study is the first to evaluate PNI changes in this patient population.

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Publication Details

Journal
BMC Cancer
Published
2025-12-02
DOI
https://doi.org/10.1186/s12885-025-15246-x
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic role of prognostic nutritional index change in patients with extensive stage small cell lung cancer treated with platinum-based chemotherapy

Emel Mutlu, Mevlüde İnanç, Sedat Tarık Fırat, Ramazan Coşar et al.
BMC Cancer
Lung Cancer Research Studies
article

Prognostic role of prognostic nutritional index change in patients with extensive stage small cell lung cancer treated with platinum-based chemotherapy

Emel Mutlu, Mevlüde İnanç, Sedat Tarık Fırat, Ramazan Coşar, Murat Eser, Oktay Bozkurt, İrfan Buğday, Ahmet Kürşad Dişli, Metin Özkan, Muhammet Cengiz
article en

Abstract

Dynamic changes in PNI are significantly associated with prognosis in extensive-stage SCLC. Patients with low pre- and post-treatment PNI values exhibited worse outcomes, while consistently high PNI predicted better survival. This study is the first to evaluate PNI changes in this patient population.

BMC CancerVol. 25(1)
Erzurum Regional Training and Research Hospital (TR), Erciyes University (TR)
Openalex Percentile: Top 48%
Lung Cancer Research Studies
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