Cell surface display of VP1 of foot-and-mouth disease virus on Saccharomyces cerevisiae

Our study indicates that yeast surface expressed VP1 elicits a superior immune response against FMDV than intracellularly expressed VP1 for immune response against FMDV, which offers a potential breakthrough in the effort to provide a simple and highly effective oral vaccine.

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Publication Details

Journal
Microbial Cell Factories
Published
2025-12-02
DOI
https://doi.org/10.1186/s12934-025-02872-0
Primary Topic
Animal Disease Management and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Cell surface display of VP1 of foot-and-mouth disease virus on Saccharomyces cerevisiae

Jeesun Chun, Yo‐Han Ko, Ngoc My Tieu Le, Dae‐Hyuk Kim
Microbial Cell Factories
Animal Disease Management and Epidemiology
article

Cell surface display of VP1 of foot-and-mouth disease virus on Saccharomyces cerevisiae

Jeesun Chun, Yo‐Han Ko, Ngoc My Tieu Le, Dae‐Hyuk Kim
article en

Abstract

Our study indicates that yeast surface expressed VP1 elicits a superior immune response against FMDV than intracellularly expressed VP1 for immune response against FMDV, which offers a potential breakthrough in the effort to provide a simple and highly effective oral vaccine.

Microbial Cell FactoriesVol. 24(1)
Jeonbuk State Institute (KR), Jeonbuk National University (KR)
National Research Foundation, National Research Foundation of Korea, Jeonbuk National University
Openalex Percentile: Top 52%
Animal Disease Management and Epidemiology
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