Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Fetal intra-abdominal testicular tumors diagnosed prenatally are exceedingly rare. However, the increasing utilization of prenatal ultrasound has led to the identification of these uncommon neoplasms. The present study reports the case of a 1-month-old male infant in whom an intra-abdominal mass was first identified on a fetal ultrasound performed at 28 weeks of gestation. Postnatally, the patient underwent complete tumor excision followed by single-stage Fowler-Stephens orchiopexy. The 7 months postoperative follow-up revealed normal findings. To the best of our knowledge, this is the first reported case of prenatally diagnosed intra-abdominal cryptorchidism associated with a mature teratoma, successfully managed with testis-sparing surgery (TSS) using Fowler-Stephens orchiopexy. The present study represents the ninth such case reported worldwide. Although neonatal testicular tumors generally require surgical excision, intraoperative frozen section analysis combined with TSS can effectively prevent unnecessary orchiectomy and enable the potential for bilateral fertility preservation.

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Publication Details

Journal
Experimental and Therapeutic Medicine
Published
2025-12-02
DOI
https://doi.org/10.3892/etm.2025.13038
Primary Topic
Testicular diseases and treatments
Type
article
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article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Deying Zhang, Shengde Wu, Xing Liu, Guanghui Wei et al.
Experimental and Therapeutic Medicine
Testicular diseases and treatments
article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Deying Zhang, Shengde Wu, Xing Liu, Guanghui Wei, Honggang Fang, Yi Hua, G. Peng
article en

Abstract

Fetal intra-abdominal testicular tumors diagnosed prenatally are exceedingly rare. However, the increasing utilization of prenatal ultrasound has led to the identification of these uncommon neoplasms. The present study reports the case of a 1-month-old male infant in whom an intra-abdominal mass was first identified on a fetal ultrasound performed at 28 weeks of gestation. Postnatally, the patient underwent complete tumor excision followed by single-stage Fowler-Stephens orchiopexy. The 7 months postoperative follow-up revealed normal findings. To the best of our knowledge, this is the first reported case of prenatally diagnosed intra-abdominal cryptorchidism associated with a mature teratoma, successfully managed with testis-sparing surgery (TSS) using Fowler-Stephens orchiopexy. The present study represents the ninth such case reported worldwide. Although neonatal testicular tumors generally require surgical excision, intraoperative frozen section analysis combined with TSS can effectively prevent unnecessary orchiectomy and enable the potential for bilateral fertility preservation.

Experimental and Therapeutic MedicineVol. 31(2)
Jiangxi Provincial Children's Hospital (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 43%
Testicular diseases and treatments
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