Uncontrollable Rectal Bleeding Following Wegener’s Granulomatosis: A Case Report

Wegener’s granulomatosis is an autoimmune vasculitis affecting small and medium vessels, typically involving the respiratory tract and kidneys. Gastrointestinal manifestations are rare and pose diagnostic and therapeutic challenges. A 65-year- old man presented with severe abdominal pain and melena. He developed renal failure requiring dialysis and underwent multiple plasmapheresis sessions. During hospitalization, he experienced massive rectal bleeding and suspected hemoptysis. Endoscopy and colonoscopy revealed no obvious lesions, but CT angiography demonstrated reduced abdominal blood flow, leading to surgical resection of necrotic tissue. Despite intervention, bleeding persisted, and enteroscopy showed multiple ulcers in the jejunum and ileum. Gastrointestinal bleeding in Wegener’s granulomatosis may result from vascular damage or tissue necrosis and can cause life-threatening complications such as anemia and shock. Early recognition and timely treatment are essential to reduce morbidity and mortality.