Burkitt´s Lymphoma with Prior Varicella Infection Presenting with Guillain–Barré Syndrome: A Case Report

Burkitt’s lymphoma (BL) emerges as the most prevalent subtype of non-Hodgkin lymphoma (NHL) in pediatric populations. Several studies have demonstrated a connection between certain viral infections and Burkitt’s lymphoma, suggesting a potential correlation between these factors. Although BL typically presents with lymph node involvement, neurological manifestations are quite rare. In this report, we detail the case of a 13-year-old male patient who initially presented with a varicella zoster infection, accompanied by neurological symptoms consistent with Guillain-Barré syndrome (GBS), and subsequently developed a substantial submandibular mass. Diagnostic imaging, along with biopsy, confirmed a diagnosis of high-grade B-cell lymphoma consistent with BL.