Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis

Genomics has revolutionized epidemiology and disease surveillance by providing powerful tools for identifying, tracking, and analyzing pathogens at the molecular level. This exploratory analysis examines the integration of genomic with traditional epidemiological approaches, highlighting the role of whole-genome sequencing as a key method for pathogen identification, outbreak investigation, and understanding transmission dynamics. By enabling the detection of mutations and monitoring of antimicrobial resistance, genomics allows for precise mapping of infection sources and transmission pathways, thereby improving the timeliness and accuracy of public health responses. Furthermore, genomic surveillance supports the early detection of emerging variants, such as those observed during viral outbreaks like COVID-19, facilitating proactive intervention strategies. Despite its transformative potential, challenges related to data privacy, infrastructure, and interdisciplinary collaboration persist. This analysis emphasizes the importance of genomics in building resilient surveillance systems to address future infectious disease threats and advocates for sustained investment in genomic technologies to advance global health security.

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Publication Details

Journal
Life
Published
2025-12-01
DOI
https://doi.org/10.3390/life15121848
Citations
4
Primary Topic
Zoonotic diseases and public health
Type
article
Field-Weighted Citation Impact
7.51

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article

Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis

Yeonsu Oh, Baek-Jun Kim, Thakur Dhakal, Gab‐Sue Jang et al.
4 citations
Life
Zoonotic diseases and public health
7.51
article

Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis

Yeonsu Oh, Baek-Jun Kim, Thakur Dhakal, Gab‐Sue Jang, Shraddha Tiwari
article en
4 citations

Abstract

Genomics has revolutionized epidemiology and disease surveillance by providing powerful tools for identifying, tracking, and analyzing pathogens at the molecular level. This exploratory analysis examines the integration of genomic with traditional epidemiological approaches, highlighting the role of whole-genome sequencing as a key method for pathogen identification, outbreak investigation, and understanding transmission dynamics. By enabling the detection of mutations and monitoring of antimicrobial resistance, genomics allows for precise mapping of infection sources and transmission pathways, thereby improving the timeliness and accuracy of public health responses. Furthermore, genomic surveillance supports the early detection of emerging variants, such as those observed during viral outbreaks like COVID-19, facilitating proactive intervention strategies. Despite its transformative potential, challenges related to data privacy, infrastructure, and interdisciplinary collaboration persist. This analysis emphasizes the importance of genomics in building resilient surveillance systems to address future infectious disease threats and advocates for sustained investment in genomic technologies to advance global health security.

LifeVol. 15(12)
Kangwon National University (KR), National Institute of Ecology (KR), Yeungnam University (KR)
National Institute of Ecology, Ministry of Environment
Openalex Percentile: Top 3%
Zoonotic diseases and public health
7.51
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Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis — Yeonsu Oh, Baek-Jun Kim, et al. · Life (2025) | TGRS Research Map | TGRS