Endoscopic Management of an Inflammatory Lesion Suspected of Being a Brown Tumor of the Frontal Process of the Maxilla—Case Report

The study reports a diagnostic challenge involving an inflammatory lesion mimicking a brown tumor. A 23-year-old male patient was referred for treatment of a cystic lesion in the left frontal process of the maxilla and ethmoid region. The leading symptoms were hemoptysis and chronic sinus inflammation. Endoscopic surgery was performed under general anesthesia, including curettage and drainage of the lesion into the middle nasal meatus. Histopathological examination revealed chronic inflammatory and fibrotic changes with hemosiderin deposits and CD68(+) histiocytes, findings that could suggest a brown tumor. However, subsequent laboratory investigations excluded this diagnosis. Postoperative healing was uneventful, with complete resolution of symptoms. This report highlights the importance of distinguishing inflammatory from metabolic bone lesions in the paranasal sinuses and underscores the critical role of histopathological evaluation in differentiating true neoplasms from inflammatory pseudotumors.

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Publication Details

Journal
Surgeries
Published
2025-12-02
DOI
https://doi.org/10.3390/surgeries6040107
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
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article

Endoscopic Management of an Inflammatory Lesion Suspected of Being a Brown Tumor of the Frontal Process of the Maxilla—Case Report

Tomasz Marecik, Grażyna Wyszyńska–Pawelec, Michał Gontarz, Krzysztof Gąsiorowski et al.
Surgeries
IgG4-Related and Inflammatory Diseases
article

Endoscopic Management of an Inflammatory Lesion Suspected of Being a Brown Tumor of the Frontal Process of the Maxilla—Case Report

Tomasz Marecik, Grażyna Wyszyńska–Pawelec, Michał Gontarz, Krzysztof Gąsiorowski, Jakub Bargiel
article en

Abstract

The study reports a diagnostic challenge involving an inflammatory lesion mimicking a brown tumor. A 23-year-old male patient was referred for treatment of a cystic lesion in the left frontal process of the maxilla and ethmoid region. The leading symptoms were hemoptysis and chronic sinus inflammation. Endoscopic surgery was performed under general anesthesia, including curettage and drainage of the lesion into the middle nasal meatus. Histopathological examination revealed chronic inflammatory and fibrotic changes with hemosiderin deposits and CD68(+) histiocytes, findings that could suggest a brown tumor. However, subsequent laboratory investigations excluded this diagnosis. Postoperative healing was uneventful, with complete resolution of symptoms. This report highlights the importance of distinguishing inflammatory from metabolic bone lesions in the paranasal sinuses and underscores the critical role of histopathological evaluation in differentiating true neoplasms from inflammatory pseudotumors.

SurgeriesVol. 6(4)
Jagiellonian University (PL)
Openalex Percentile: Top 46%
IgG4-Related and Inflammatory Diseases
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