Ticagrelor plus aspirin versus cilostazol plus aspirin in the acute-phase treatment of large-vessel minor stroke or TIA: A randomized controlled multi-center trial, the TACTIS trial
Combining cilostazol with aspirin in large-vessel occlusion minor ischemic stroke or TIA was as effective as ticagrelor and aspirin in preventing recurrent stroke, MI, and death due to vascular events, but resulted in significantly lower rates of hemorrhagic complications.
Authors
- Dalia Maher Samy
- Sherihan Rezk Ahmed (ORCID: https://orcid.org/0000-0001-7129-1819)
- Ahmed Zaki Omar Akl (ORCID: https://orcid.org/0009-0009-3047-0154)
- Romany Adly yousef
- Mohamed G. Zeinhom (ORCID: https://orcid.org/0000-0002-0337-349X)
- Youssry Salah Shafiq Kerolos
- Hamada Zehry
- Ashraf Tawfik Soliman (ORCID: https://orcid.org/0000-0002-9585-9461)
- Essam E. Khalil (ORCID: https://orcid.org/0000-0001-8309-1718)
- Mohamed Ismaiel (ORCID: https://orcid.org/0000-0002-5840-5137)
- Ahmed Ahmed Mohamed Kamal Ebied (ORCID: https://orcid.org/0000-0002-2692-141X)
- Ghada Abd El Wahab Khalil
- Mohamed Fouad Elsayed Khalil
- Mohamed Elshafei (ORCID: https://orcid.org/0000-0002-4266-5620)
- Ahmed Mohamed Ali Daabis
- Ahmad Galal Mohammed Mohammed Elmesallami
Institutions
- Ain Shams University (EG)
- Damietta University (EG)
- Kafrelsheikh University (EG)
- Al Noor Hospitals (AE)
- Cairo University (EG)
- Zagazig University (EG)
- Egypt Nanotechnology Center (EG)
- Shaikh Khalifa Medical City (AE)
- Dubai Hospital (AE)
- Al Ain Hospital (AE)
- Abu Dhabi Health Services (AE)
- Khoula Hospital (OM)
- Shebin Teaching Hospital (EG)
Publication Details
- Journal
- International Journal of Stroke
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1177/17474930251406865
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00