Identification of Plasma Biomarkers in Untreated Schizophrenia Patients Using Untargeted Lipid Metabolomics
The findings reveal lipid metabolism dysregulation as a potential pathophysiological mechanism of schizophrenia. The identified metabolites, such as AcCa and phosphatidylcholine, serve as promising biomarkers for the diagnosis and symptom evaluation, suggesting their direct involvement in the disease's pathogenesis.
Authors
- Long Chen (ORCID: https://orcid.org/0000-0003-1110-6495)
- Yanyu Wang (ORCID: https://orcid.org/0000-0001-5731-3225)
- Haonan Jiang (ORCID: https://orcid.org/0009-0001-0108-730X)
- Zhiqiang Wang (ORCID: https://orcid.org/0009-0005-3306-649X)
- Xulai Zhang
Institutions
- Anhui Medical University (CN)
- Anhui Mental Health Center (CN)
- Fourth Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Neuropsychiatric Disease and Treatment
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ndt.s537721
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00