Comparative Cardiovascular Safety of Duloxetine and Gabapentin in Patients with Hip Osteoarthritis
Duloxetine was generally associated with increased CV risks, while a lower risk of AMI and no significant increase in mortality were observed compared to gabapentin. Our subgroup analysis further suggests that when potential confounding from preexisting CVDs was minimized, duloxetine was associated with incident CV complications in patients without prior CVDs.
Authors
- Yeo Jin Choi (ORCID: https://orcid.org/0000-0002-0635-4374)
- Suhyeon Moon (ORCID: https://orcid.org/0000-0002-2811-7986)
- Sooyoung Shin (ORCID: https://orcid.org/0000-0003-2388-1122)
- Eunjung Choo (ORCID: https://orcid.org/0000-0002-6529-0657)
Institutions
- Kyung Hee University (KR)
- Ajou University (KR)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jpr.s557621
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Ajou University
- Ministry of Food and Drug Safety
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea