Sequential Treatment of Generalized Pustular Psoriasis Combined with Bullous Pemphigoid Using Spesolimab and Dupilumab: A Case Report and Literature Review
This case highlights the potential of sequential spesolimab and dupilumab therapy as an effective and safe approach for managing GPP coexisting with BP. Targeting distinct inflammatory pathways may provide a new treatment option for complex dermatological comorbidities.
Authors
- Haijun Yu (ORCID: https://orcid.org/0000-0002-5346-7830)
- Zhihong Zhang (ORCID: https://orcid.org/0000-0002-3749-4716)
- Ying Wang (ORCID: https://orcid.org/0000-0002-1407-2668)
- Lei Wang (ORCID: https://orcid.org/0000-0001-5349-6298)
- Yanping Bai (ORCID: https://orcid.org/0000-0003-3365-4409)
- Haoyu Yang (ORCID: https://orcid.org/0000-0002-0644-6930)
Institutions
- China-Japan Friendship Hospital (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Case Reports in Dermatology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1159/000547774
- Primary Topic
- Autoimmune Bullous Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00