Evidence for sult1st6y as a Major Candidate Sex-Determining Gene in Pacific Bluefin Tuna
Our results collectively suggest that sult1st6y is at the top of the molecular cascade that regulates gonadal sex differentiation. Sult1st6y may trigger testicular differentiation by deactivating estrogens, although its biochemical activity should be examined. This study provides evidence that sult1st6y is a major candidate sex-determining gene in tuna.
Authors
- Takao Hayashida (ORCID: https://orcid.org/0000-0001-9507-0375)
- Yoji Nakamura (ORCID: https://orcid.org/0000-0003-2650-1770)
- Yukinori Kazeto
- Satoshi Soma (ORCID: https://orcid.org/0009-0000-9400-3701)
Institutions
- Japan Fisheries Research and Education Agency (JP)
Publication Details
- Journal
- Sexual Development
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1159/000549624
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00