Viral traits from deep mutational scanning and socio-demographic context predict SARS-CoV-2 lineage fitness across diverse countries

Viral traits and socio-economic context jointly shaped SARS-CoV-2 variant fitness. Immune escape was more influential for lineage growth in low-resource settings, emphasizing the need for equitable vaccine access and targeted interventions against the spread of immune-escape variants.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-11-28
DOI
https://doi.org/10.1016/j.ijid.2025.108260
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Viral traits from deep mutational scanning and socio-demographic context predict SARS-CoV-2 lineage fitness across diverse countries

Hsiang‐Yu Yuan, Zhaojun Ding
International Journal of Infectious Diseases
SARS-CoV-2 and COVID-19 Research
article

Viral traits from deep mutational scanning and socio-demographic context predict SARS-CoV-2 lineage fitness across diverse countries

Hsiang‐Yu Yuan, Zhaojun Ding
article en

Abstract

Viral traits and socio-economic context jointly shaped SARS-CoV-2 variant fitness. Immune escape was more influential for lineage growth in low-resource settings, emphasizing the need for equitable vaccine access and targeted interventions against the spread of immune-escape variants.

International Journal of Infectious DiseasesVol. 163
City University of Hong Kong (HK)
City University of Hong Kong
Openalex Percentile: Top 56%
SARS-CoV-2 and COVID-19 Research
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