Identification of Risk Factors for Relapse following Rituximab Therapy in Children with Steroid-Sensitive Nephrotic Syndrome
Baseline memory B-cell and NK-cell levels (pre-RTX), as well as IgG levels at 3 months post-RTX, were identified as predictive biomarkers for the 2-year relapse risk following RTX therapy. These findings may contribute to the development of personalized RTX treatment strategies.
Authors
- Dan Wu (ORCID: https://orcid.org/0000-0002-0241-4691)
- Hejia Zhang (ORCID: https://orcid.org/0000-0001-5222-5277)
- Lin Hua (ORCID: https://orcid.org/0000-0001-6309-3572)
- Ling Chen (ORCID: https://orcid.org/0000-0002-0293-5841)
- Zhi Chen (ORCID: https://orcid.org/0000-0002-3991-8383)
- Xiaorong Liu (ORCID: https://orcid.org/0000-0002-8912-5066)
- Yue Xi (ORCID: https://orcid.org/0000-0003-2789-7674)
- Lei Lei (ORCID: https://orcid.org/0009-0000-3826-9169)
Institutions
- Capital Medical University (CN)
- Beijing Children’s Hospital (CN)
Publication Details
- Journal
- Kidney Diseases
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1159/000548505
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00