Knocking down tumor suppressor gene PTPRG enhances axonal regeneration of dorsal root ganglion neurons

These findings identify PTPRG as a novel negative regulator of axonal regeneration, expanding the repertoire of molecules that can be manipulated to improve functional recovery after nerve injuries.

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Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2025-11-13
DOI
https://doi.org/10.3389/fcell.2025.1698864
Primary Topic
Nerve injury and regeneration
Type
article
Field-Weighted Citation Impact
0.00

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article

Knocking down tumor suppressor gene PTPRG enhances axonal regeneration of dorsal root ganglion neurons

Qian Zhao, Yi Sheng, Lan Zhang, Jingjing Li et al.
Frontiers in Cell and Developmental Biology
Nerve injury and regeneration
article

Knocking down tumor suppressor gene PTPRG enhances axonal regeneration of dorsal root ganglion neurons

Qian Zhao, Yi Sheng, Lan Zhang, Jingjing Li, Peng Yang
article en

Abstract

These findings identify PTPRG as a novel negative regulator of axonal regeneration, expanding the repertoire of molecules that can be manipulated to improve functional recovery after nerve injuries.

Frontiers in Cell and Developmental BiologyVol. 13
Nantong University (CN), Affiliated Hospital of Nantong University (CN)
Government of Jiangsu Province
Openalex Percentile: Top 59%
Nerve injury and regeneration
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