Isocitrate Dehydrogenase-Mutant WHO Grade 4 Astrocytoma with BCOR Alteration: Case Report
This case represents the first report of a BCOR ITD in an IDH-mutant WHO grade 4 astrocytoma. The discovery expands the molecular spectrum of high-grade astrocytomas and highlights the need for further research into the biological, prognostic, and therapeutic significance of BCOR alterations in these tumors.
Authors
- Huda Alghefari
- Saleh Baeesa (ORCID: https://orcid.org/0000-0002-3053-7912)
- Badr Hafiz (ORCID: https://orcid.org/0000-0003-3311-8091)
- Alaa Alkhotani (ORCID: https://orcid.org/0000-0002-6528-9592)
- Fahad Okal
- Eyad Faizo
- Maher Kurdi (ORCID: https://orcid.org/0000-0002-8979-3849)
- Ahmed A. Najjar (ORCID: https://orcid.org/0000-0002-0132-5072)
- Faisal Mrair
- Ahmad Albeshri
Institutions
- King Abdulaziz University (SA)
- Umm al-Qura University (SA)
- Taibah University (SA)
- King Faisal Specialist Hospital & Research Centre (SA)
- King Abdulaziz Medical City (SA)
- University of Tabuk (SA)
Publication Details
- Journal
- Case Reports in Oncology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1159/000548555
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00