Power Spectral Slope as a Novel Brain Functional Marker for Major Depressive Disorder
This study demonstrates that MDD is characterized by more negative PSS in key affective regions. The normalization effect of ventral striatum spectral slope following antidepressant treatment suggests a region-specific response. Taken together, the findings suggest that PSS may serve as a novel brain functional marker for MDD.
Authors
- Kaini Qiao (ORCID: https://orcid.org/0000-0003-0115-6413)
- Xuequan Zhu (ORCID: https://orcid.org/0000-0001-5551-2810)
- Zhenxiang Zang (ORCID: https://orcid.org/0000-0002-6865-054X)
- Gang Wang (ORCID: https://orcid.org/0000-0001-6500-5863)
- Yanyu Wang (ORCID: https://orcid.org/0000-0001-5731-3225)
- Huimin Zhou (ORCID: https://orcid.org/0000-0001-8297-2003)
- Zhi Yang
- Jingjing Zhou (ORCID: https://orcid.org/0000-0002-4808-7294)
Institutions
- Capital Medical University (CN)
- Beijing Anding Hospital (CN)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.bpsgos.2025.100623
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00