Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess
These findings provide mechanistic insights into sex-dimorphic developmental reprogramming of fetal brain by maternal estradiol excess. They establish a framework for developing targeted interventions against gestational endocrine disruption-induced neurodevelopmental disorders.
Authors
- Yu Zhang (ORCID: https://orcid.org/0000-0001-9909-9503)
- X. Chen
- Jin Li (ORCID: https://orcid.org/0000-0002-1340-7761)
- Huihui Wang (ORCID: https://orcid.org/0000-0001-5781-0504)
- Zhe Wei (ORCID: https://orcid.org/0000-0002-1032-5525)
- Chengliang Zhou (ORCID: https://orcid.org/0000-0002-9402-1077)
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Renji Hospital (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s13293-025-00792-7
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00