Hemodynamic and microcirculatory early adaptations following transcatheter aortic valve implantation ( <scp>TAVI</scp> ): A physiological pilot study
TAVI induces rapid macro- and microcirculatory changes, with early tissue perfusion improvement despite transient microcirculatory reserve impairment. VEGF dynamics were associated with postoperative complications, suggesting endothelial activation as a marker of vulnerability and linking baseline endothelial status to vascular adaptation and outcomes.
Authors
- Raoul Schorer (ORCID: https://orcid.org/0000-0001-7848-7021)
- Ivo Neto Silva (ORCID: https://orcid.org/0000-0002-7391-786X)
- Stanislas Abrard (ORCID: https://orcid.org/0000-0002-5883-1777)
- Nikolaos Stergiopulos (ORCID: https://orcid.org/0000-0002-0519-0160)
- Karim Bendjelid (ORCID: https://orcid.org/0000-0002-7921-7207)
- Stéphane Noble
- Georgios Rovas (ORCID: https://orcid.org/0000-0002-4020-6826)
- Dionysios Adamopoulos (ORCID: https://orcid.org/0000-0003-4356-823X)
- Andres Hagerman (ORCID: https://orcid.org/0009-0005-7826-8546)
- Bernardo Bollen Pinto (ORCID: https://orcid.org/0000-0002-1281-543X)
- Sarah Mauler
- Christoph Ellenberger (ORCID: https://orcid.org/0000-0002-6076-303X)
- Stéphane Bar
Institutions
- Université Claude Bernard Lyon 1 (FR)
- University of Geneva (CH)
- Inserm (FR)
- Hôpital Beau-Séjour (CH)
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Hospices Civils de Lyon (FR)
- University Hospital of Geneva (CH)
- Health Services and Performance Research Laboratory (FR)
- University Hospitals Geneva Medical Center (US)
- École Polytechnique Fédérale de Lausanne (CH)
- Geneva College (US)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1111/eci.70156
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Faculté de Médecine, Université de Genève