Neonatal BCG vaccination to prevent respiratory infections in the first 5 years of life: results from the MIS BAIR randomised controlled trial
In a low-mortality setting, there was not clear evidence that neonatal BCG vaccination significantly reduces the incidence of early life hospitalisation for LRTI, infections or respiratory illness. The ability to detect any effect of BCG may have been limited by the increasing missing data over the course of follow-up.
Authors
- Kate Francis (ORCID: https://orcid.org/0000-0002-1751-5313)
- Kaya Gardiner (ORCID: https://orcid.org/0000-0001-9796-4567)
- Frank Shann (ORCID: https://orcid.org/0000-0002-9899-1804)
- Emily K. Forbes (ORCID: https://orcid.org/0000-0003-2372-0126)
- Mike South (ORCID: https://orcid.org/0000-0002-5530-2722)
- Nicole L. Messina (ORCID: https://orcid.org/0000-0001-8404-4462)
- Susan Donath (ORCID: https://orcid.org/0000-0003-2489-3977)
- Dan Casalaz
- Roy M. Robins‐Browne (ORCID: https://orcid.org/0000-0001-9179-7884)
- Laure F. Pittet (ORCID: https://orcid.org/0000-0002-2395-4574)
- Peter Vuillermin (ORCID: https://orcid.org/0000-0002-6580-0346)
- Katie L. Flanagan (ORCID: https://orcid.org/0000-0002-1575-1953)
- Anne‐Louise Ponsonby (ORCID: https://orcid.org/0000-0002-6581-3657)
- Nigel Curtis (ORCID: https://orcid.org/0000-0003-3446-4594)
Institutions
- University of Tasmania (AU)
- Barwon Health (AU)
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- Mercy Hospital for Women (AU)
- Peter Doherty Institute (AU)
- Victorian Clinical Genetics Services (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Vaccine
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127958
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00