Gypenoside LI Inhibits Renal Cancer Proliferation by Affecting LipidMetabolism through the Upregulation of Dual-Specificity Phosphatase 1
Gyp LI upregulates DUSP1 to suppress the metabolism of choline, linoleic acid, and alpha-linolenic acid, ultimately suppressing the incidence and progression of ccRCC.
Authors
- Xiuming Li (ORCID: https://orcid.org/0000-0002-9616-723X)
- Yujie Wei
- P. C. Sun (ORCID: https://orcid.org/0009-0009-5347-7631)
- Shuai Li (ORCID: https://orcid.org/0000-0002-3492-7176)
- Jiahui Yu (ORCID: https://orcid.org/0000-0003-4329-2739)
- Anxin Wang (ORCID: https://orcid.org/0000-0001-7095-6022)
- Chang Zhou
Institutions
- Chengde Medical University (CN)
- Chengde Medical University (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-11-29
- DOI
- https://doi.org/10.2174/0113862073437377251103074331
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00