Integrated Evaluation of IL-8 Levels and the In Silico and In Vitro Effects of Ellagic Acid against Extended-spectrum β-lactamase in Biofilm-formingKlebsiella pneumoniae Isolated from Urinary Tract Infections
IL-8 is a valuable biomarker for ESBL-producing K. pneumoniae infection. Ellagic acid reduces biofilm formation and targets bacterial resistance and virulence proteins, supporting its potential as a natural anti-virulence agent against multidrug-resistant K. pneumoniae.
Authors
- Ali Hazim Abdulkareem
- Samer N. Khalaf
- Haneen Emad Khadum
- Mohammed Salih Al-Janaby (ORCID: https://orcid.org/0000-0002-2831-9246)
Institutions
- University of Anbar (IQ)
- University Of Fallujah (IQ)
Publication Details
- Journal
- Reviews on Recent Clinical Trials
- Published
- 2025-11-29
- DOI
- https://doi.org/10.2174/0115748871349421251105115035
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 0.00