Detecting Local Myocardial Spatiotemporal Repolarization Gradients With Clinical Mapping Arrays
Repol<sup>Loc</sup> has higher sensitivity to local spatiotemporal repolarization heterogeneities and alternans than traditional ARI. Although ARI only correlates with uniformly distributed changes in repolarization in the entire myocardium, Repol<sup>Loc</sup> also provided accurate regional gradient assessment and duration alternans of repolarization. These findings suggest ARI has significant far-field contamination and Repol<sup>Loc</sup> may provide a better clinical mapping tool for spatiotemporal repolarization gradient mapping.
Authors
- K. Nanthakumar (ORCID: https://orcid.org/0000-0001-8035-5829)
- Stéphane Massé (ORCID: https://orcid.org/0000-0003-4081-0406)
- John Asta
- Vijay S. Chauhan (ORCID: https://orcid.org/0000-0001-9264-5073)
- Patrick F.H. Lai (ORCID: https://orcid.org/0000-0002-8355-7183)
- Christopher Labos (ORCID: https://orcid.org/0000-0002-6814-3134)
- Abhishek Bhaskaran (ORCID: https://orcid.org/0000-0003-2963-4907)
- Praloy Chakraborty (ORCID: https://orcid.org/0000-0002-5054-9136)
- Paul Dorian (ORCID: https://orcid.org/0000-0002-8244-3520)
- Tasnia Subha (ORCID: https://orcid.org/0009-0000-2663-5985)
- Yusuf Abderrahman
- Golnaz Mokhtar-Sasani
Institutions
- University Health Network (CA)
- Norwegian Womens Public Health Association (NO)
- McGill University (CA)
Publication Details
- Journal
- Circulation Arrhythmia and Electrophysiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1161/circep.125.014213
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00