Dihydromyricetin Remodels the Tumor Immune Microenvironment in Hepatocellular Carcinoma: Development and Validation of a Prognostic Model
This study developed a prognostic model based on the potential target genes of DHM in HCC. This model effectively stratifies HCC patients, identifying a high-risk subgroup characterized by an immunosuppressive microenvironment. These findings provide a theoretical foundation for exploring DHM as a promising natural adjuvant for cancer immunotherapy.
Authors
- Jingkun Mao
- Fei Lan (ORCID: https://orcid.org/0000-0003-3672-1283)
- Xiao Jian Tan (ORCID: https://orcid.org/0000-0003-1038-3933)
- Wei Li (ORCID: https://orcid.org/0000-0001-9931-5990)
- Pengfei Li (ORCID: https://orcid.org/0000-0002-2572-5935)
- Chao Gu (ORCID: https://orcid.org/0000-0002-7128-8721)
- Yang Xu (ORCID: https://orcid.org/0009-0009-5974-047X)
Institutions
- Tarim University (CN)
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3390/cimb47121010
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00