Solvent-free <i>in situ</i> self-nanoemulsifying dissolving microneedles for rapid and safe transdermal treatment of acute pain with plant-derived eugenol
Surfactant-free, self-nanoemulsifying dissolving microneedles enable rapid transdermal eugenol delivery via in situ nano-emulsification, enhancing analgesic efficacy and bypassing GI risks associated with oral NSAIDs.
Authors
- De‐Shen Wang (ORCID: https://orcid.org/0000-0001-9657-4380)
- Chao Luo (ORCID: https://orcid.org/0000-0001-8497-8548)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-4007-1108)
- Shuai Qian (ORCID: https://orcid.org/0000-0003-1961-4128)
- Mi Tang (ORCID: https://orcid.org/0000-0002-1594-9599)
- Yuanfeng Wei (ORCID: https://orcid.org/0000-0002-9710-4425)
- Jiaqi Liu (ORCID: https://orcid.org/0000-0002-9775-2342)
- Jianjun Zhang (ORCID: https://orcid.org/0000-0002-1774-5135)
- Peiya Shen (ORCID: https://orcid.org/0000-0002-3644-8988)
Institutions
- China Pharmaceutical University (CN)
- Simcere Pharmaceutical (China) (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1039/d5gc06106g
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00