Spectrum of Movement Disorders in Early‐Onset Hereditary Spastic Paraplegia: A Study of 428 Cases
Movement disorders are common, genotype-specific, and clinically impactful features of childhood-onset HSP. Routine screening and genotype-tailored management of movement disorders, especially dystonia, may improve functional outcomes and quality of life. © 2025 International Parkinson and Movement Disorder Society.
Authors
- Kathryn Yang (ORCID: https://orcid.org/0009-0004-6892-5189)
- Sally E. Carty (ORCID: https://orcid.org/0000-0002-8288-3884)
- Marcondes C. França (ORCID: https://orcid.org/0000-0003-0898-2419)
- Amy Tam (ORCID: https://orcid.org/0000-0003-2072-3436)
- Darius Ebrahimi‐Fakhari (ORCID: https://orcid.org/0000-0002-0026-4714)
- Zainab Zaman
- Carelis González‐Salazar (ORCID: https://orcid.org/0000-0003-2300-682X)
- Julian E. Alecu (ORCID: https://orcid.org/0000-0002-1420-9775)
- Matthias Kieslich (ORCID: https://orcid.org/0000-0001-7525-795X)
- Filippo Maria Santorelli (ORCID: https://orcid.org/0000-0002-1359-9062)
- Katerina Bernardi (ORCID: https://orcid.org/0009-0004-3387-7623)
- Vicente Quiroz (ORCID: https://orcid.org/0009-0005-9212-0943)
- Luca Schierbaum (ORCID: https://orcid.org/0009-0002-4884-9647)
- Dario Resch
- Habibah A.P. Agianda (ORCID: https://orcid.org/0000-0002-5346-5026)
- Nicole Battaglia (ORCID: https://orcid.org/0009-0008-9751-4580)
- Joshua Rong (ORCID: https://orcid.org/0009-0001-5277-5794)
Institutions
- Goethe University Frankfurt (DE)
- Boston Children's Hospital (US)
- Harvard University (US)
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Fondazione Stella Maris (IT)
- University Hospital Frankfurt (DE)
- Hospital de Clínicas da Unicamp (BR)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1002/mds.70141
- Primary Topic
- Hereditary Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00