Cell instructive hydrogels functionalized with polymerized DNA nanostructures
Novel hyaluronic acid hydrogels functionalized with polymerized DNA nanostructures using rolling circle amplification were developed. These hydrogels exhibited enhanced cell attachment and proliferation through functional DNA-mediated interactions. The system maintained favorable physicochemical properties and enhanced interactions with biological interfaces, demonstrating potential for advanced 3D cell culture applications.
Authors
- Young Hoon Roh (ORCID: https://orcid.org/0000-0002-7396-4156)
- Keonwook Nam (ORCID: https://orcid.org/0000-0002-9797-7509)
- Sumin Han (ORCID: https://orcid.org/0000-0003-0861-7980)
- Kyungjik Yang (ORCID: https://orcid.org/0009-0006-6342-9666)
- Young‐Min Kim (ORCID: https://orcid.org/0000-0003-3220-9004)
- Sunghoon Kim (ORCID: https://orcid.org/0000-0002-1645-7473)
- Joohyun Oh (ORCID: https://orcid.org/0000-0001-9457-2357)
Institutions
- Yonsei University (KR)
Publication Details
- Journal
- Nanoscale Horizons
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1039/d5nh00521c
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00