Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients

Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.