Acute inflammatory demyelinating polyneuropathy (Guillain—Barré syndrome)

Guillain-Barré syndrome is an acute immune-mediated polyradiculoneuropathy, which is the most common cause of acute paralysis and requires intensive therapy in one third of cases. Considering the fact that the disease is rare and characterized by low mortality, morphological changes in it are described rather modestly, based on isolated examples. The article analyzes literature data and our own observations of Guillain-Barré syndrome, including an analysis of clinical data, treatment, and the nature of structural changes based on routine, histochemical, and immunohistochemical studies.