Do the pharmacokinetics of statins explain psychiatric symptom improvement from adjunctive statin prescribing in severe mental illness? Three target trial emulation studies
There is currently not enough evidence to guide the prescription of statins for psychiatric symptom improvement in patients with SMI. If there is an effect of statins, it may be through specific statin-antipsychotic combinations.
Authors
- Sarah Hardoon (ORCID: https://orcid.org/0000-0002-3044-3713)
- David Osborn (ORCID: https://orcid.org/0000-0003-2519-1539)
- Kenneth K. C. Man (ORCID: https://orcid.org/0000-0001-8645-1942)
- Alvin Richards‐Belle (ORCID: https://orcid.org/0000-0001-8577-9380)
- Naomi Launders (ORCID: https://orcid.org/0000-0003-4241-938X)
- Ian Chi Kei Wong (ORCID: https://orcid.org/0000-0001-8242-0014)
- Joseph Hayes (ORCID: https://orcid.org/0000-0003-2286-3862)
Institutions
- Department of Health (CN)
- University College London Hospitals NHS Foundation Trust (GB)
- Aston University (GB)
- University College London (GB)
- University of Hong Kong (HK)
- Camden and Islington NHS Foundation Trust (GB)
Publication Details
- Journal
- BMJ Mental Health
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjment-2025-302124
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00