Identification of candidate long non-coding RNAs and mRNAs associated with heart aging in mice
Cardiac aging is characterized by structural and functional remodeling, accompanied by transcriptional reprogramming involving both lncRNAs and mRNAs. These changes offer insights into potential molecular mechanisms and provide candidate regulatory targets for diagnosis and intervention in age-related heart disease.
Authors
- Jianguo Jia (ORCID: https://orcid.org/0000-0002-6993-6080)
- Yangli Ye (ORCID: https://orcid.org/0000-0003-1875-3863)
- Zheng Kuai (ORCID: https://orcid.org/0000-0003-1866-5564)
- Xiaoyi Zhang
- Zheng Li (ORCID: https://orcid.org/0000-0001-6024-0194)
- Ling Li (ORCID: https://orcid.org/0000-0002-8617-1673)
- Jianhui Zhang
- Yu Hu (ORCID: https://orcid.org/0000-0003-3883-3887)
- Yongle Chen (ORCID: https://orcid.org/0000-0002-2366-8711)
- Lihong Gao
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-12-02
- DOI
- https://doi.org/10.7717/peerj.20433
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00