Clinical utility of ECAP dosing in a real-world population delivered via EVOKE therapy: the ECAP study
EVOKE therapy was associated with clinically meaningful improvements in a real-world chronic pain population across different subgroups and disease pathologies, with effects observed at trial end reproduced at post-implant visit.
Authors
- J. Carson Smith (ORCID: https://orcid.org/0000-0001-6142-0920)
- Maged Guirguis (ORCID: https://orcid.org/0000-0003-4700-2698)
- Rui Duarte (ORCID: https://orcid.org/0000-0001-6485-7415)
- Nicole Soliday
- Shrif Costandi (ORCID: https://orcid.org/0000-0002-0864-9846)
- Steven M. Falowski (ORCID: https://orcid.org/0000-0003-3996-087X)
- Dawood Sayed (ORCID: https://orcid.org/0000-0001-8867-2140)
- Jan Willem Kallewaard (ORCID: https://orcid.org/0000-0002-7681-1796)
- Nagy Mekhail (ORCID: https://orcid.org/0000-0002-3823-9610)
- David J. Rosenfeld (ORCID: https://orcid.org/0000-0002-8721-7020)
- Angela Leitner (ORCID: https://orcid.org/0000-0002-5037-1825)
- Christopher Lam (ORCID: https://orcid.org/0000-0002-2848-6255)
- Gregory L. Smith (ORCID: https://orcid.org/0000-0002-4595-9149)
- Ahmed M. Raslan
- Jill Pope
- Julie G. Pilitsis (ORCID: https://orcid.org/0000-0002-6488-9692)
- Erin Hanson
- Chau Vu (ORCID: https://orcid.org/0009-0009-9488-1550)
- Andras Laufer
- Michael Sprintz
- Usman Latif (ORCID: https://orcid.org/0000-0002-5683-5547)
- Robert Heros
- Johnathan Goree (ORCID: https://orcid.org/0000-0003-0548-852X)
- Jarna R Shah (ORCID: https://orcid.org/0000-0002-2412-2796)
- Timothy R. Deer (ORCID: https://orcid.org/0000-0001-8907-7730)
- Salim M. Hayek (ORCID: https://orcid.org/0000-0001-7936-017X)
- Steven M. Rosen
- Todd A. Bromberg
- Jonathan M. Hagedorn (ORCID: https://orcid.org/0000-0003-1039-8166)
- J Tate
- Aaron Calodney (ORCID: https://orcid.org/0000-0003-0509-6868)
- Erika Petersen (ORCID: https://orcid.org/0000-0002-8548-1450)
- Shivanand P. Lad (ORCID: https://orcid.org/0000-0003-4991-5319)
- Robert M. Levy (ORCID: https://orcid.org/0000-0002-2736-4096)
- Nathan Miller (ORCID: https://orcid.org/0000-0002-8934-7857)
- Ronald B. Boeding
- Denis G. Patterson
- Atish Patel
- Jessica Jameson
- Ajay Antony
Institutions
- Cleveland Clinic (US)
- Mayo Clinic (US)
- Ochsner Health System (US)
- University of Nevada, Reno (US)
- University of Arizona (US)
- University of Kansas (US)
- University of Liverpool (GB)
- Oregon Health & Science University (US)
- University Hospitals of Cleveland (US)
- North Idaho College (US)
- Erasmus MC (NL)
- The University of Kansas Health System (US)
- Lancaster General Hospital (US)
- Evolve Restorative Center (US)
- Coeur d Alene Arthritis Clinic (US)
- Saluda Medical (Australia) (AU)
- Precision Spine (United States) (US)
- The Centers (US)
- Duke Medical Center (US)
- Spinal Diagnostics and Treatment Center (US)
- Spinal Elements (United States) (US)
- University of Minnesota Health Maple Grove Clinics (US)
- The Spine & Nerve Centers of the Virginias (US)
- Amsterdam University Medical Centers (NL)
- Rijnstate Hospital (NL)
- Duke University Hospital (US)
- Neurological Surgery (US)
- Behavioral Health Services (US)
- International Neuromodulation Society (US)
- The Orthopaedic Institute (US)
- Delaware Valley College (US)
- Albany Medical Center Hospital (US)
- University of Arkansas for Medical Sciences (US)
- University of Amsterdam (NL)
Publication Details
- Journal
- Regional Anesthesia & Pain Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/rapm-2025-107051
- Citations
- 1
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Boston Scientific Corporation
- Stryker
- Saluda Medical
- SPR Therapeutics
- Nevro
- National Institutes of Health
- Allergan