A prognostic model for uveal melanoma in Asian populations: a comparative analysis of clinical features and gene expression patterns using the TRACE and TCGA data

This cross-racial UM study reveals significant molecular and immune differences, indicating that Asian UM may be more responsive to immunotherapy The population-specific prognostic model improves our understanding of molecular differences in Asian and Caucasian UM, warranting further validation in multiethnic cohorts.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-12-02
DOI
https://doi.org/10.1186/s12886-025-04509-7
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A prognostic model for uveal melanoma in Asian populations: a comparative analysis of clinical features and gene expression patterns using the TRACE and TCGA data

Yueming Liu, Li Yang, Yang-Xu Tao, Zhaoxun Feng et al.
BMC Ophthalmology
Ocular Oncology and Treatments
article

A prognostic model for uveal melanoma in Asian populations: a comparative analysis of clinical features and gene expression patterns using the TRACE and TCGA data

Yueming Liu, Li Yang, Yang-Xu Tao, Zhaoxun Feng, Wenbin Wei, Jingting Luo, Qiong Yang, Haowen Li, Yuning Chen, Jingying Xiu
article en

Abstract

This cross-racial UM study reveals significant molecular and immune differences, indicating that Asian UM may be more responsive to immunotherapy The population-specific prognostic model improves our understanding of molecular differences in Asian and Caucasian UM, warranting further validation in multiethnic cohorts.

BMC OphthalmologyVol. 26(1)
Beijing Tongren Hospital (CN), University of Ottawa (CA)
Openalex Percentile: Top 48%
Ocular Oncology and Treatments
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