Anti-skin aging effects of black ginseng extracts through regulating inflammatory factors and the CLOCK–ERK pathway in mice
The present study demonstrated that the extracts of BG and PT played similar roles in an anti-skin aging. The possible mechanism involves the inhibition of oxidative stress (OS) and inflammation, which can lead to change clock genes and drive epidermal differentiation of epidermal stem cells (ESCs) through the activation of ERK to cause ESCs depletion and skin aging.
Authors
- Meng Qiu (ORCID: https://orcid.org/0000-0002-0178-3479)
- Liang Hao (ORCID: https://orcid.org/0000-0001-5658-9975)
- Haiying Ma (ORCID: https://orcid.org/0000-0002-1314-7816)
- Chenghong Zhang (ORCID: https://orcid.org/0000-0001-8826-5895)
- Yufei Huang
- Bing Wang (ORCID: https://orcid.org/0000-0002-7028-389X)
- Jin Yu (ORCID: https://orcid.org/0000-0003-2049-3677)
- Jinyun Liu (ORCID: https://orcid.org/0000-0002-4763-2684)
Institutions
- Dalian Medical University (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.jgr.2025.11.014
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00