Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome
Our data support a role for low-grade systemic inflammation, especially elevated hsCRP and IL-6, in fatigue and depressive symptoms during sarcoidosis remission. Further research integrating inflammatory, oxidative, metabolic, and neuroendocrine pathways is needed to elucidate fatigue pathogenesis and develop targeted interventions. IL-6 may represent a potential biomarker of fatigue in sarcoidosis. These findings highlight the importance of persistent low-grade inflammation and may guide the development of future therapeutic strategies.
Authors
- Elżbieta Małujło-Balcerska (ORCID: https://orcid.org/0000-0002-0061-6353)
- Witold Górski
- Adam Białas (ORCID: https://orcid.org/0000-0002-3501-167X)
- Łukasz Gwadera (ORCID: https://orcid.org/0000-0002-9724-2078)
- Anna Kumor‐Kisielewska
- Karol Bączek (ORCID: https://orcid.org/0009-0006-1587-0115)
Institutions
- Medical University of Lodz (PL)
- National University of Medical Sciences (PK)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jir.s549445
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00