Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

In a large US registry, women with axSpA were more likely to discontinue TNFi and IL-17i than men. Larger studies with longer follow-up since treatment approval are needed to confirm the lack of sex differences in JAKi discontinuation as this group could be underpowered.

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Publication Details

Journal
Arthritis Care & Research
Published
2025-12-02
DOI
https://doi.org/10.1002/acr.70001
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

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Arthritis Care & Research
Spondyloarthritis Studies and Treatments
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Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Katherine D. Wysham, Namrata Singh, Jinoos Yazdany, Lianne S. Gensler, Gabriela Schmajuk, Rachael Stovall, Eric T. Roberts, Cinthia Blat, Jean W. Liew, Janna Friedly
article en

Abstract

In a large US registry, women with axSpA were more likely to discontinue TNFi and IL-17i than men. Larger studies with longer follow-up since treatment approval are needed to confirm the lack of sex differences in JAKi discontinuation as this group could be underpowered.

Arthritis Care & Research
Boston University (US), Public Policy Institute of California (US), University of California, San Francisco (US), University of Washington (US), VA Puget Sound Health Care System (US), San Francisco VA Health Care System (US), Seattle University (US)
Rheumatology Research Foundation, National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Openalex Percentile: Top 46%
Spondyloarthritis Studies and Treatments
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