A rare case report of prosthetic loosening secondary to diffuse non-pigmented villonodular synovitis after bilateral total knee arthroplasty
Final post-revision radiographs validated successful stabilization following both revisions. This longitudinal bilateral case uniquely demonstrates synovial hyperplasia as a replicable driver of aseptic loosening independent of PVNS, highlights heterogeneous progression kinetics and recurrence risk between limbs despite unilateral intervention, and confirms the consistent efficacy of revision arthroplasty for this specific pathology.
Authors
- Li‐Chen Lin (ORCID: https://orcid.org/0000-0002-2325-2257)
- Lei Li (ORCID: https://orcid.org/0009-0003-3146-0261)
- Haina Jiang
- H.Y. Yu (ORCID: https://orcid.org/0000-0002-1527-8756)
- Hongjiang Jiang (ORCID: https://orcid.org/0000-0001-8366-9030)
- Wei Yan (ORCID: https://orcid.org/0000-0001-5575-7017)
- Ke Cai (ORCID: https://orcid.org/0000-0002-6954-0588)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Weihai Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3389/fsurg.2025.1709479
- Primary Topic
- Musculoskeletal synovial abnormalities and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00