Risk factors for mechanical complications in very elderly patients with acute myocardial infarction

This study identifies ventricular aneurysm as the dominant mechanical complication in very elderly AMI patients, establishes a paradoxical protective role of hypertension history, and proposes a distinct risk profile integrating hemodynamic status, neutrophilic inflammation, and metabolic derangement. These findings are hypothesis-generating and highlight a potentially valuable stratification tool that warrants prospective validation in external cohorts before clinical application.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-12-02
DOI
https://doi.org/10.3389/fmed.2025.1714080
Primary Topic
Cardiac Structural Anomalies and Repair
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk factors for mechanical complications in very elderly patients with acute myocardial infarction

Wei Yuan, Luqin Yan
Frontiers in Medicine
Cardiac Structural Anomalies and Repair
article

Risk factors for mechanical complications in very elderly patients with acute myocardial infarction

Wei Yuan, Luqin Yan
article en

Abstract

This study identifies ventricular aneurysm as the dominant mechanical complication in very elderly AMI patients, establishes a paradoxical protective role of hypertension history, and proposes a distinct risk profile integrating hemodynamic status, neutrophilic inflammation, and metabolic derangement. These findings are hypothesis-generating and highlight a potentially valuable stratification tool that warrants prospective validation in external cohorts before clinical application.

Frontiers in MedicineVol. 12
First Affiliated Hospital of Xi'an Jiaotong University (CN)
Openalex Percentile: Top 43%
Cardiac Structural Anomalies and Repair
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