Saliva phosphorylated tau concentration is not associated with Alzheimer’s disease, cerebrospinal fluid or blood biomarkers
For this reason, we conclude that saliva p-tau181 is not acceptable as a biomarker for AD.
Authors
- Joel Simren
- Nicholas James Ashton (ORCID: https://orcid.org/0000-0002-3579-8804)
- Gunnar Brinkmalm (ORCID: https://orcid.org/0000-0001-6958-2393)
- Jörg Hanrieder (ORCID: https://orcid.org/0000-0001-6059-198X)
- Kaj Blennow (ORCID: https://orcid.org/0000-0002-1890-4193)
- Juan Lantero‐Rodriguez (ORCID: https://orcid.org/0000-0002-7426-678X)
- Peter Høgh (ORCID: https://orcid.org/0000-0002-8478-8098)
- Steen Gregers Hasselbalch (ORCID: https://orcid.org/0000-0003-4750-4911)
- Thomas K. Karikari (ORCID: https://orcid.org/0000-0003-1422-4358)
- Helena Sophia Gleerup (ORCID: https://orcid.org/0000-0001-7470-4818)
- Anja Hviid Simonsen (ORCID: https://orcid.org/0000-0002-5461-162X)
- Laia Montoliu‐Gaya (ORCID: https://orcid.org/0000-0001-7684-6318)
- Federica Sanna
- Srinivas Koutarapu (ORCID: https://orcid.org/0000-0002-4355-6733)
- Henrik Zetterberg
Institutions
- University of Copenhagen (DK)
- Alzheimer's Association (US)
- University of Wisconsin–Madison (US)
- University of Cagliari (IT)
- Washington University in St. Louis (US)
- Roskilde Sygehus (DK)
- Region Zealand (DK)
- Sahlgrenska University Hospital (SE)
- Banner Health (US)
- Copenhagen University Hospital (DK)
- Zealand University Hospital (DK)
- Institute for Neurodegenerative Disorders (US)
- UK Dementia Research Institute (GB)
- Banner Sun Health Research Institute (US)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3389/fnins.2025.1718237
- Citations
- 1
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Familjen Erling-Perssons Stiftelse
- Cure Alzheimer's Fund
- Stiftelsen för Gamla Tjänarinnor
- EU Joint Programme – Neurodegenerative Disease Research
- National Institute for Health and Care Research
- University College London
- European Commission
- Gentofte Hospital
- Lundbeckfonden
- Hjärnfonden
- Vetenskapsrådet
- Augustinus Fonden
- Rigshospitalet
- Sjællands Universitetshospital
- H. Lundbeck A/S
- UK Dementia Research Institute
- HORIZON EUROPE Framework Programme