Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations
This preliminary study provides meaningful evidence supporting the potential of suPAR as a marker of disease severity in SSc and the impact of method-related differences in the levels of suPAR.
Authors
- Francesca Wanda Rossi (ORCID: https://orcid.org/0000-0002-5430-032X)
- Amato de Paulis (ORCID: https://orcid.org/0000-0003-0347-2540)
- Filomena Napolitano (ORCID: https://orcid.org/0000-0003-1925-9912)
- Nunzia Montuori (ORCID: https://orcid.org/0000-0001-8697-986X)
- Gabriele Mignogna
- Ilaria Mormile
Institutions
- World Allergy Organization (US)
- Federico II University Hospital (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1697785
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00