Clinical outcomes and early- prognostic biomarkers of primary biliary cholangitis with ductopenia
Ductopenia is relatively common in patients with PBC, and its prevalence significantly increases with disease progression. Ductopenia was an independent risk factor for the occurrence of liver-related adverse events in patients with PBC. ANA(≥1:1000), TBIL, GGT, and ALB are early predictive biomarkers for ductopenia in patients with PBC.
Authors
- Lingna Lv
- Zefeng Liu (ORCID: https://orcid.org/0000-0002-7565-5381)
- Huilan Ye
- Hongxing Liu (ORCID: https://orcid.org/0000-0002-0547-5721)
- Huiguo Ding
- Ying Han (ORCID: https://orcid.org/0000-0003-3046-9507)
- Wen-Juan Wang (ORCID: https://orcid.org/0000-0003-2892-1330)
- Zhang Guo (ORCID: https://orcid.org/0000-0002-3644-8902)
- Jing Chang (ORCID: https://orcid.org/0000-0002-5119-535X)
Institutions
- Sun Yat-sen University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1680942
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Capital Medical University