Upright positioning enhances beam angle optimization and organ sparing in head and neck carbon-ion radiotherapy with fixed-beam systems
The anterior beams at 15°in the upright setup (U15) showed the best balance of robustness and OAR sparing, making it the preferred option. The 15°-angled supine setup (S15) is a practical alternative. S0 and U45 are not recommended due to inferior robustness and higher brainstem dose, respectively.
Authors
- Yinxiangzi Sheng (ORCID: https://orcid.org/0000-0002-3552-9786)
- Jingyi Cheng (ORCID: https://orcid.org/0000-0001-8974-4791)
- Liwen Zhang (ORCID: https://orcid.org/0000-0001-6203-1978)
- Rong Zhou (ORCID: https://orcid.org/0000-0002-8469-1464)
- Shiya Huang
Institutions
- Sichuan University (CN)
- Shanghai Innovative Research Center of Traditional Chinese Medicine (CN)
- Fudan University Shanghai Cancer Center (CN)
- Shanghai Genon Biological Products (China) (CN)
- Center for High Pressure Science & Technology Advanced Research (CN)
- Shanghai Institute of Hematology (CN)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s13014-025-02755-z
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Science and Technology Major Project
- National Key Research and Development Program of China