HIV infection and immunosenescence: challenges and intervention strategies
Despite growing insights into HIV-associated immune ageing, there is still no universally applicable biomarker of immunosenescence. This gap underscores the need to develop robust, population-tailored biomarker panels and targeted interventions for PWH, to support integrated strategies that combine antiretroviral therapy with immune restoration and anti-ageing approaches, ultimately improving immune health and quality of life.
Authors
- Qianqian Xu (ORCID: https://orcid.org/0000-0003-1393-6644)
- Alex Siu Wing Chan (ORCID: https://orcid.org/0000-0003-4420-8789)
- Christiane Moog (ORCID: https://orcid.org/0000-0002-0916-156X)
- Junyan Jin
- Tong Zhang (ORCID: https://orcid.org/0000-0002-5725-9510)
- Xin Zhang (ORCID: https://orcid.org/0000-0001-8520-1060)
- Bin Su (ORCID: https://orcid.org/0000-0001-5140-0440)
- Wei Xia (ORCID: https://orcid.org/0000-0002-2032-2133)
- Aiwei Zhu
Institutions
- Hong Kong Baptist University (HK)
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s12916-025-04545-6
- Citations
- 1
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.25